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The average increase in body weight in studies was less than 5 pounds (2,25 kg) over 2 years. However, current studies are not conclusive because they do not compare the weight of women using implants with a control group of women not using the implant. Possible weight gain: Some women may experience slight weight gain when using the implant. Correct subdermal insertion over the triceps muscle reduces the risk of these events. There have been rare reports of implants having reached the lung via the pulmonary artery. It can be located using traditional X-ray or CT-scan because of the inclusion of barium sulphate. Rods can be located only through high-frequency ultrasound or magnetic resonance imaging (MRI). It is possible that insertion in the same site as a previous implant increases the likelihood of migration. Migration: Although very rare, the rod can sometimes move slightly within the arm. An Australian study reported 84 pregnancies as a result of such failure. In some cases, a serious complication occurs when the provider fails to insert, and the rod is left in the inserter. However, there are some rare complications that can occur, such as infection or expulsion.
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Insertion complications: Some minor side effects such as bruising, skin irritation, or pain around the insertion site are common. After removal, bleeding patterns return to previous patterns in most women. While these patterns are not dangerous, they are the most common reason that women give for discontinuing the use of the implant. However, other women may experience this bleeding pattern through all five years of use. For some women, prolonged bleeding will decline after the first three months of use. Irregular bleeding and spotting: Many women will experience some type of irregular, unpredictable, prolonged, frequent, or infrequent bleeding. See also: Desogestrel § Side effects, and Progestin § Side effects A single implant is approved for three years with data showing effectiveness for five years.
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In comparison, tubal sterilization has a failure rate of 0.5% and IUDs have a failure rate of 0.2–0.8%. Other studies have found some failures with this method, some attributed to failures of the method itself and others to improper placement, drug interactions, or conception prior to method insertion. Studies of one type, which include over 2,467 women-years of exposure, found no pregnancies. The failure rate of the implants is 0.05% for both perfect use and typical use because the method requires no user action after placement. Įtonogestrel birth control implants are a type of long-acting reversible contraception, which has been shown to be one of the most effective form of birth control. Įtonogestrel is used in hormonal contraception in form of the etonogestrel contraceptive implant and the contraceptive vaginal ring (brand names NuvaRing, Circlet), the latter in combination with ethinylestradiol.
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Ī closely related and more widely known and used progestin, desogestrel, is a prodrug of etonogestrel in the body. Etonogestrel implants are approved in more than 90 countries and used by about three million women globally as of 2010. It became available in the United States in 2006. Įtonogestrel was patented in 1972 and introduced for medical use in 1998. It has very weak androgenic and glucocorticoid activity and no other important hormonal activity. It works by stopping ovulation, thickening the mucus around the opening of the cervix, and altering the lining of the uterus. Etonogestrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. Side effects of etonogestrel include menstrual irregularities, breast tenderness, mood changes, acne, headaches, vaginitis, and others. Following removal, fertility quickly returns. Etonogestrel is effective as a means of birth control within 8 hours of insertion and lasts at least three or four years with some data showing effectiveness for five years. It is available as an implant placed under the skin of the upper arm under the brand names Nexplanon and Implanon, and in combination with ethinylestradiol, an estrogen, as a vaginal ring under the brand names NuvaRing and Circlet. May cause irregular or prolonged bleedingĮtonogestrel is a medication which is used as a means of birth control for women.